From Wiki

Wine - Windows Emulator

Wine is used for running Windows based programs on Linux. www.winehq.com Wine is not very stable, and as a result, I strongly suggest you look for a similar program with similar functionality. Do a "apt-cache search program" to search for packages/programs.

Install Wine

apt-get install wine

apt-get install winesetuptk
//This is a gui for setting up wine for a user. It sets up a fake_windows main folder etc.

apt-get install wine-utils
//This provides tools such as "regedit" which can simply be run as "regedit" from the cmdline to show and allow editing of the emulated Windows registry.

Run a Windows Program/Installer in Wine

wine programinstall.exe

wine notepad.exe

Note wine is not very stable for some programs. There are a list of programs and how well they run on the Wine website at: http://appdb.winehq.org/appbrowse.php